According to a double-blind trial of 150 subjects in the British Journal of Dermatology in 2024, after continuous use of sleeping gloves containing the neuroamide formula for 7 days, the average thickness of the stratum corneum in the palms of the subjects decreased by 19.8μm (baseline value 65.2μm), and the skin elastic modulus increased by 23%. It was significantly better than the control group that only used hand cream (with an increase of only 7%). Thermal imaging monitoring shows that the internal humidity of the gloves remained stable at 72%±3%RH within 2 hours after wearing, and the penetration rate of the moisturizing components was accelerated to 0.12mg/cm²·h, which is 1/5 of the normal evaporation. The FDA medical device database of the United States shows that the moisture permeability of registered medical-grade sleeping gloves should be ≤25g/m²·24h. This parameter design can reduce the loss of epidermal moisture by 41%.
Data from market analysis firm Statista shows that the global market size of sleeping gloves reached 430 million US dollars in 2023, among which the repurchase rate of products with silver ion antibacterial coatings was as high as 68%. Take the best-selling brand HandCure Pro as an example. Its patented 3D weaving technology (with a wire diameter of 0.08mm and a pore density of 380 holes /cm²) can control the local temperature within the optimal absorption range of 33-34℃. Confirmed by laser Doppler detection, the microcirculation blood flow velocity increased to 1.8mm/s 4 hours after use, which was 27% faster than the bare-hand state. The consumer tracking survey found that among users who wore it for 6-8 hours every night, 93% felt a reduction in roughness within 3 days. Measured by the Cutometer MPA580 instrument, the skin smoothness index (R7 value) increased by an average of 0.43 (baseline value 2.15).
The cost-benefit model shows that the average daily usage cost of the medical silicone sleeping gloves with a unit price of $29 is approximately $0.16, saving 69.8% compared to using high-end repair cream (an average daily cost of $0.53). Tests conducted by the Materials Laboratory of Seoul National University in South Korea have shown that the breathability index (MVTR) of the new TPU material gloves reaches 3200g/m²·24h. While maintaining an internal humidity of 65%, it can control the evaporation of sweat to below 0.9g/h, preventing excessive skin hydration. This is in complete agreement with the requirement in the ISO 13485 medical device standard of 2022 that “the deviation of moisture permeability of contact products should be ≤15%”.
However, clinical data show that approximately 18% of users suffer from compressive edema due to improper size selection (with an error exceeding ±5mm). A study by the Technical University of Munich found that when the internal pressure of gloves exceeds 1.5kPa, the perfusion volume of capillaries decreases by 34%, affecting the delivery of nutrients. Therefore, the EU CE certification mandates that products be marked with pressure distribution maps. The palm pressure gradient design for high-quality products should be within the range of 0.3 to 0.8kPa. The report from the third-party testing agency Intertek pointed out that for the sleeping gloves product certified by OEKO-TEX, the detection amount of allergens was lower than 0.03μg/cm², which was 50 times higher than the safety threshold of uncertified products.
From a biomechanical perspective, the ergonomic tailoring adopted by current advanced products can maintain the range of motion of finger joints at over 85%, avoiding any impact on sleep quality. The nanofiber membrane (pore size 0.2μm) gloves developed by Toray Group of Japan still maintain an antibacterial rate of 99.7% after 300 machine washes. Its moisture regulation ability keeps the epidermal pH value stable at 5.5±0.2, which is more suitable for stratum corneum repair than ordinary cotton gloves (pH fluctuation up to 1.2). Experimental data shows that when used in combination with 5% urein cream, the penetration of the active ingredient within 8 hours reaches 82mg, which is 3.7 times the absorption amount when applied alone.